Anthem Biosciences Limited IPO

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The company is an innovation-led and technology-focused Contract Research, Development, and Manufacturing Organization (CRDMO) that provides fully integrated services across the drug development value chain—from discovery to development and commercial manufacturing. With a strong focus on both New Chemical Entities (NCEs) and New Biological Entities (NBEs), it serves a diverse global customer base, including emerging biotech firms and large pharmaceutical companies.

 Business Segments

A. CRDMO Services

i) End-to-end drug development services for both small molecules and biologics
ii) Capabilities spanning target identification, preclinical development, clinical trials (Phase I-III), and commercial-scale manufacturing.

iii) Strong presence in advanced modalities including RNAi, ADCs, peptides, lipids, and oligonucleotides
iv) Manufacturing capabilities include custom synthesis, flow chemistry, fermentation, and biotransformation

B. Specialty Ingredients

i) Manufacture and sale of fermentation-based APIs such as probiotics, enzymes, peptides, nutritional actives, vitamin analogues, and biosimilars.

ii) Serves both regulated markets (U.S., Europe) and semi-regulated markets (India, LATAM, Asia, Middle East)

Innovation & Technological Leadership

The company is a technology leader, being among the first in India to enter ADC development and biotransformation. It has adopted green chemistry techniques like micellar technology, flow chemistry, and pincer catalysis, and built advanced platforms in RNAi, peptide, and oligonucleotide manufacturing—backed by consistent R&D investments.

Differentiated Business Model

i) Focused Fee-For-Service (FFS) model ideal for small and emerging biotech customers
ii) High success rate (95.59%) in FFS projects
iii) 87.11% of CRDMO customers in FY25 were small/emerging biotech companies
iv) Strategic positioning in underserved modalities like ADCs and RNAi

Global Customer Base

As of March 31, 2025, the company served over 550 customers across 44 countries, including the U.S., Europe, and Japan. Its top 10 clients contributed over 77% of FY25 revenue, supported by a strategic partnership with DavosPharma that strengthened its presence in the U.S. biotech market.

Manufacturing Infrastructure

The company operates two manufacturing facilities, with a third under construction and expected by H1 FY26. Fermentation capacity stands at 142 kL, set to expand to 182 kL—the highest among Indian CRDMOs. Custom synthesis capacity will reach 425 kL post-expansion. Facilities are approved by global regulators including the U.S. FDA, ANVISA, PMDA, and TGA.

Objects of the Anthem Biosciences Limited IPO:

The Company will not receive any proceeds from the Offer; all proceeds, net of offer-related expenses and taxes, will be received by the Selling Shareholders.

Anthem Biosciences Limited IPO Details:

Open Date: Jul 14 2025
Close Date: Jul 16 2025
Total Shares: 5,95,61,404
Face Value: ₹ 2 Per Equity Share
Issue Type: Book Building
Issue Size: 3395 Cr.
Lot Size: 26 Shares
Issue Price: ₹ 540 - 570 Per Equity Share
Listing At: NSE,BSE

Promoters And Management:

1. Ajay Bhardwaj, 64, is the Chairman, Managing Director, and CEO of the Company. He holds a Bachelor's in Chemical Engineering from IIT Delhi and a Master's from Louisiana State University. With over 40 years of experience in life sciences, contract research, and pharmaceutical manufacturing, he has previously held leadership roles at Max India and Biocon. 2. Ganesh Sambasivam, 59, is the Whole-time Director and Chief Scientific Officer. He holds degrees in Chemistry from the University of Madras and University of Pune, including a Ph.D. He has over 31 years of experience in process R&D and was formerly the Chief Scientific Officer at Syngene International. 3. K. Ravindra Chandrappa, 58, is the Whole-time Director and Chief Operating Officer. A Chemical Engineering graduate from Bangalore University, he oversees R&D, manufacturing, quality, and regulatory functions. With 25+ years of experience, he specializes in large-scale operations and global quality compliance in the pharma and biopharma sectors.

Financials of Anthem Biosciences Limited IPO:

Particulars(In cr) FY 2024-25 FY 2023-24    FY 2022-23
Revenue from Operations 1,844.55 1,419.37 1,056.92
Revenue from R&D services 200.57 185.57 173.14
Revenue from D&M 1,305.51 897.59 634.95
Revenue from specialty ingredients 338.46 336.20 248.83
EBITDA 683.78 519.95 446.05
EBITDA Margins 36.81% 36.25% 41.53
PAT 451.25 367.31 385.18
PAT Margins 23.38% 24.77% 33.97%
Post Tax ROCE 26.88% 25.71% 31.69%
Operating Cash Flows 418.33 140.15 305.98

Comparison With Peers:

FY2025
Companies Revenue (In Cr.) EBITDA Margins PAT Margins D/E Ratio ROCE MCap (In Cr.) P/E
Anthem Biosciences 1,844.55 36.81% 23.38% 0.04 26.88% 32,011 70.94
Syngene International 3,642 29% 13.61% 0.12 13.50% 25,474 53.80
Sai Life Sciences Limited 1,642 24% 10.53% 0.13 13.90% 16,407 94.60
Cohance Lifesciences Limited 1,198 31% 22.12% 0.16 16.80% 38,356 145
Divi’s Laboratories 9,360 Cr. 32% 23.40% 0.00 20.40% 1,82,644 83.30

Registrar of Anthem Biosciences Limited IPO:

  1. Kfin Technology Private Limited

Discussion on Anthem Biosciences Limited IPO:

1 Comment

    🔬 Company Overview: Anthem Biosciences
    Anthem Biosciences is a Contract Research, Development, and Manufacturing Organization (CRDMO) focused on innovation and technology in biosciences.

    Offers fully integrated services in drug discovery, development, and manufacturing.

    Its top 5 molecules together have generated sales of over ₹96,000 crore globally.

    Exports constitute ~80% of revenue, primarily from the US, Europe, and Japan.

    Has a 19-year track record of consistent profitability since inception.

    Co-founded by Ajay Bharadwaj after his 21-year stint at Biocon.

    💼 Business Model
    Anthem helps global pharma and biotech companies, especially smaller, VC-backed firms, in discovering and developing new molecules.

    These smaller firms often lack their own lab infrastructure and rely on Anthem’s extensive R&D capabilities.

    Company offers end-to-end solutions: from initial research → development → manufacturing → supply for trials → commercial supply.

    Relationships are sticky and long-term: average relationship with top 10 clients is 12 years.

    Positioned as a research powerhouse with ~1500 scientists/engineers out of 2000 employees.

    Focus on New Chemical Entities (NCEs) and New Biological Entities (NBEs), not generics.

    🧪 Scientific Edge
    Anthem uniquely combines biology and chemistry capabilities—an intersection that few Indian companies operate in.

    Known for solving complex chemistry problems through biology.

    Expertise in cutting-edge modalities:

    Antibody-Drug Conjugates (ADCs)

    Peptides

    RNAi & Oligonucleotides

    Lipid nanoparticles

    Currently supplying API or advanced intermediates for 10 novel molecules, 4 of which are blockbuster drugs.

    16 additional molecules are in late-stage clinical trials or regulatory filing phase.

    💰 IPO Details
    IPO Opens: July 14, 2025

    IPO Closes: July 16, 2025

    Price Band: ₹540 – ₹570 per share

    Lot Size: 26 shares (₹14,820 approx.)

    Issue Size: ~₹3,400 crore

    Entirely an Offer for Sale (OFS)—no primary infusion

    Implied Market Cap: ₹32,000 crore

    Post-IPO Promoter Holding will reduce to 74.6% (from 76.8%)

    🧾 Reason for OFS, Not Primary
    Anthem is a cash-rich company:

    EBITDA Margin: ~36.8%

    PAT Margin: ~24%

    19 years of positive cash flow

    No need for primary capital—internal accruals are sufficient for expansion.

    Existing investor True North PE (entered in 2021) is taking a partial exit.

    Other sellers: employees, strategic US marketing partner (Davos Pharma), and minor promoter dilution to meet SEBI norms. Main Promoter Mr. Ajay Bhardwaj not selling even one share in this OFS.

    🏭 Manufacturing & Infrastructure
    Operates 3 facilities, 2 are USFDA-approved (Successful audits by USFDA).

    Recently commissioned 3rd facility and starting 4th facility for expansion.

    Fully integrated capabilities to supply products across clinical and commercial stages.

    📈 Financials & Growth Outlook
    Sustained 20% YoY growth over the last 5 years.

    EBITDA Margins have remained stable at ~36%+ despite slight dip from earlier 41%.

    Plans further expansion to meet rising demand from novel molecules.

    Confident of sustaining current margins due to:

    Healthy pipeline of commercial-stage molecules.

    Visibility into future revenue from ongoing trials.

    Strong demand for high-end CDMO services in complex drugs.

    🎯 Key Differentiators
    One of India’s very few companies strong in both chemistry and biology.

    Long-term relationships with global clients backed by trust, quality, and scientific excellence.

    Positioned strongly in next-gen drug development platforms.

    Strategic foresight into emerging therapeutic modalities.

    📝 Closing Remarks
    Anthem Biosciences has built a reputation as India’s premier CRDMO.

    The IPO is not just a liquidity event—it signals entry into public capital markets while continuing strong fundamentals.

    Promoters and key shareholders retain confidence by not selling shares during IPO.

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